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The Ópera do Tejo (Portuguese: [ˈɔpɨɾɐ du ˈtɛʒu], Tagus Opera) or Real Casa da Ópera (Royal Opera House) was a luxurious opera house in Lisbon, Portugal. It was inaugurated on March 31, 1755, and destroyed by the major earthquake on November 1 of the same year.
The theater was opened with the opera Alessandro nell’Indie by Davide Perez, with libretto by Pietro Metastasio. Before its destruction, the opera also premiered two operas by Antonio Mazzoni with libretti also by Pietro Metastasio, La clemenza di Tito (June 6) and Antigono (October 16).