112 may refer to:

• 112 (number), the natural number following 111 and preceding 113
• 112 (band), an American R&B quartet from Atlanta, Georgia
  • 112 (album), album from the band of the same name
• 112 (emergency telephone number), the standard emergency phone number in the European Union and on GSM cellphones
• 112 BC, a year
• AD 112, a year of the Julian calendar
• Copernicium, an element with atomic number 112
• 112 (MBTA bus)
• 112 (New Jersey bus)
• KFM 112M aircraft engine
• Thai Criminal Code section 112, see Lèse majesté in Thailand
• 112 Iphigenia, a main-belt asteroid