The 1968 United States Senate election in Oklahoma was held November 3, 1968. Incumbent Democratic U.S. Senator Mike Monroney was running for re-election to a fourth term, but was defeated by Republican Henry Bellmon. This election was the first time since 1942 that a Republican won a United States Senate election in Oklahoma and the first time since 1920 that a Republican won a United States Senate election in Oklahoma for this seat.

1968 United States Senate election in Oklahoma

← 1962 November 3, 1968 1974 →

Nominee Henry Bellmon Mike Monroney Party Republican Democratic Popular vote 470,120 419,658 Percentage 51.71% 46.16%

County results Bellmon:      40-50%      50-60%      60-70%      70-80% Monroney:      40–50%      50–60%      60–70%

U.S. senator before election Mike Monroney Democratic Elected U.S. Senator Henry Bellmon Republican