British Drug Houses had operated in Poole for 40 years.^[4] The plant at West Quay Road was constructed in 1982.^[5]

At about 7:30 pm emergency services were called to a fire at an industrial unit on West Quay Road in Poole. The warehouse was operated by BDH and stood adjacent to the Port of Poole, and close to residential and commercial areas in Old Poole.^[7] The fire was discovered in an oxidising storeroom, and it had spread to the adjacent area containing flammable liquids.^[8]

There were flames up to 100 ft (30 m) high and flaming drums full of liquids were sent into the air and rained down on neighbouring streets.^[9] Missiles from the fire spread 50 m (150 ft), and there was off site damage to 100 m (350 ft) away.^[10] A fireball was witnessed and a plume of yellow-brown smoke was seen rising over Poole Old Town.^[11]

An evacuation began at 7.45pm, affecting a one square mile radius in Poole Town Centre. Nearby tower blocks were emptied, and terraced streets were searched. People were sent to the Arts Centre, Sports Centre and the Arndale Centre (now Dolphin Shopping Centre). The evacuation was organised by Station Manager Gordon Hughes. In November 1988, he became only the 2nd recipient of the Chief Officer's Commendation.

14 people were taken to Poole General Hospital. Local residents were not allowed to return to their homes until 5.30 am the next day. The Health and Safety Executive, on the scene that morning, said the devastation would make an investigation of the cause virtually impossible. Street furniture and traffic lights had melted and windows were smashed. The smoke was analysed to have contained hydrogen chloride. Pollution of watercourses, including Poole Harbour, was also of concern. Authorities said that luck had kept the injuries minor, as barrels containing cyanide did not explode and the wind blew the toxic smoke offshore.^[12]

Member of Parliament for Poole John Ward asked the Parliamentary Under Secretary of State for Employment Patrick Nicholls to set up a public inquiry into the incident. The minister confirmed that the Health and Safety Executive would carry out a full investigation into the cause of the fire.^[13] The results of the investigation were published and publicised at a press conference held on 17 October 1988. The minister also confirmed that the BDH facilities at West Quay Road had been inspected 15 times between 1979 and 1988.^[14]

In 1997, BDH closed the West Quay Road plant and half of their local workforce were made redundant. The factory was pulled down and the land is now occupied by Poole Lifeboat Station, other buildings making up the Royal National Lifeboat Institution headquarters, and the Lifeboat College which opened in 2004.^[15]