2,5-Dimethoxy-4-nitroamphetamine

Summary

2,5-Dimethoxy-4-nitroamphetamine (DON) is a psychedelic drug and amphetamine. It is an analog of DOM and DOB. It is also closely related to 2C-N.

2,5-Dimethoxy-4-nitroamphetamine
Names
Preferred IUPAC name
1-(2,5-Dimethoxy-4-nitrophenyl)propan-2-amine
Identifiers
  • 67460-68-8 checkY
3D model (JSmol)
  • Interactive image
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ChEMBL
  • ChEMBL8301 checkY
ChemSpider
  • 95083 checkY
  • 105432
UNII
  • 3FIV60666J checkY
  • DTXSID00874243 Edit this at Wikidata
  • InChI=1S/C11H16N2O4/c1-7(12)4-8-5-11(17-3)9(13(14)15)6-10(8)16-2/h5-7H,4,12H2,1-3H3 checkY
    Key: JQJRESSXOVAECC-UHFFFAOYSA-N checkY
  • InChI=1/C11H16N2O4/c1-7(12)4-8-5-11(17-3)9(13(14)15)6-10(8)16-2/h5-7H,4,12H2,1-3H3
    Key: JQJRESSXOVAECC-UHFFFAOYAW
  • COc1cc(c(cc1CC(C)N)OC)N(=O)=O
  • [O-][N+](=O)c1cc(OC)c(cc1OC)CC(N)C
Properties
C11H16N2O4
Molar mass 240.259 g·mol−1
Melting point 206 to 207 °C (403 to 405 °F; 479 to 480 K) (hydrochloride)
231-232 °C ((R)-isomer)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Chemistry edit

DON is in a class of compounds commonly known as alpha-methyl phenethylamines, or amphetamines and the full chemical name is 1-(2,5-dimethoxy-4-nitrophenyl)propan-2-amine. It has a stereocenter.

Effects edit

In his book PiHKAL, Alexander Shulgin lists a dosage of DON as being 3-4.5 mg orally with amphetamine-like stimulation lasting 8–15 hours.[1]

Dangers edit

The toxicity of DON is not known.

Legality edit

DON is unscheduled in the United States, but because of its close similarity in structure and effects to DOM and DOB, possession and sale of DON may be subject to prosecution under the Federal Analog Act.[citation needed] DON is listed as a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act after the table of contents of PiHKAL and TiHKAL were added to the schedules.

See also edit

References edit

  1. ^ a b DON Entry in PiHKAL