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2-phospho-L-lactate transferase 
Summary
2-phospho-L-lactate transferase (EC 2.7.8.28, LPPG:Fo 2-phospho-L-lactate transferase, LPPG:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase, MJ1256, lactyl-2-diphospho-(5')guanosine:Fo 2-phospho-L-lactate transferase, CofD) is an enzyme with systematic name (2S)-lactyl-2-diphospho-5'-guanosine:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase.[1][2] This enzyme catalyses the following chemical reaction
| 2-phospho-L-lactate transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.8.28 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2S)-lactyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin GMP + coenzyme F420-0
This enzyme is involved in the biosynthesis of coenzyme F420.
References edit
- ^ Graupner M, Xu H, White RH (March 2002). "Characterization of the 2-phospho-L-lactate transferase enzyme involved in coenzyme F(420) biosynthesis in Methanococcus jannaschii". Biochemistry. 41 (11): 3754–61. doi:10.1021/bi011937v. PMID 11888293.
- ^ Forouhar F, Abashidze M, Xu H, Grochowski LL, Seetharaman J, Hussain M, Kuzin A, Chen Y, Zhou W, Xiao R, Acton TB, Montelione GT, Galinier A, White RH, Tong L (April 2008). "Molecular insights into the biosynthesis of the F420 coenzyme". The Journal of Biological Chemistry. 283 (17): 11832–40. doi:10.1074/jbc.m710352200. PMC 2431047. PMID 18252724.
External links edit
- 2-phospho-L-lactate+transferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
