23S_rRNA_(guanine2069-N7)-methyltransferase Knowpia

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23S rRNA (guanine²⁰⁶⁹-N⁷)-methyltransferase
23S rRNA (guanine2069-N7)-methyltransferase
Identifiers
EC no.	2.1.1.264
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
PMC
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PMC	articles
PubMed	articles
NCBI	proteins

23S rRNA (guanine²⁰⁶⁹-N⁷)-methyltransferase (EC 2.1.1.264, rlmK (gene), 23S rRNA m7G2069 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine²⁰⁶⁹-N⁷)-methyltransferase.^[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine²⁰⁶⁹ in 23S rRNA

\rightleftharpoons

S-adenosyl-L-homocysteine + N⁷-methylguanine²⁰⁶⁹ in 23S rRNA

The enzyme specifically methylates guanine²⁰⁶⁹ at position N⁷ in 23S rRNA.

References edit

^ Kimura S, Ikeuchi Y, Kitahara K, Sakaguchi Y, Suzuki T, Suzuki T (May 2012). "Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity". Nucleic Acids Research. 40 (9): 4071–85. doi:10.1093/nar/gkr1287. PMC 3351187. PMID 22210896.

External links edit

23S+rRNA+(guanine2069-N7)-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[1] Kimura S, Ikeuchi Y, Kitahara K, Sakaguchi Y, Suzuki T, Suzuki T (May 2012). "Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity". Nucleic Acids Research. 40 (9): 4071–85. doi:10.1093/nar/gkr1287. PMC 3351187. PMID 22210896.

[1]

Summary

References edit

External links edit