23S_rRNA_(uracil747-C5)-methyltransferase Knowpia

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23S rRNA (uracil⁷⁴⁷-C⁵)-methyltransferase
23S rRNA (uracil747-C5)-methyltransferase
Identifiers
EC no.	2.1.1.189
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
PMC
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PMC	articles
PubMed	articles
NCBI	proteins

23S rRNA (uracil⁷⁴⁷-C⁵)-methyltransferase (EC 2.1.1.189, YbjF, RumB, RNA uridine methyltransferase B) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (uracil⁷⁴⁷-C⁵)-methyltransferase.^[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + uracil⁷⁴⁷ in 23S rRNA

\rightleftharpoons

S-adenosyl-L-homocysteine + 5-methyluracil⁷⁴⁷ in 23S rRNA

The enzyme specifically methylates uracil⁷⁴⁷ at C⁵ in 23S rRNA.

References edit

^ Madsen CT, Mengel-Jørgensen J, Kirpekar F, Douthwaite S (August 2003). "Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry". Nucleic Acids Research. 31 (16): 4738–46. doi:10.1093/nar/gkg657. PMC 169892. PMID 12907714.

External links edit

23S+rRNA+(uracil747-C5)-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[1] Madsen CT, Mengel-Jørgensen J, Kirpekar F, Douthwaite S (August 2003). "Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry". Nucleic Acids Research. 31 (16): 4738–46. doi:10.1093/nar/gkg657. PMC 169892. PMID 12907714.

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Summary

References edit

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