4-acetoxy-MET (4-acetoxy-N-methyl-N-ethyltryptamine), also known as 4-AcO-MET or metacetin, is a hallucinogenic tryptamine. It is the acetate ester of 4-HO-MET, and a homologue of 4-AcO-DMT. It is a novel compound with very little history of human use.[1] It is sometimes sold as a research chemical by online retailers.
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Other names | 4-Acetoxy-MET; Metacetin; 4-Acetoxy-N-methyl-N-ethyltryptamine |
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Formula | C15H20N2O2 |
Molar mass | 260.337 g·mol−1 |
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Due to its similarity to the psilocin prodrug 4-AcO-DMT, which is deacetylated to form psilocin in vivo,[2][3] it is expected that 4-AcO-MET is also quickly hydrolyzed into 4-HO-MET by serum esterases, but human studies concerning the metabolic fate of this drug are lacking.
In the United States, 4-Acetoxy-MET is not scheduled. It may be considered an analogue of psilocin, a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical purposes could be considered a crime under the Federal Analogue Act.[4]
In Switzerland, 4-Acetoxy-MET is a controlled substance under Verzeichnis E.[5]
In the United Kingdom, 4-Acetoxy-MET is a Class A drug in the UK because it is an ester of the drug 4-HO-MET, which is a Class A drug under the tryptamine catch-all clause.[6]