4-Chloromethcathinone (also known as 4-CMC and Clephedrone) is a stimulant drug of the cathinone class that has been sold online as a designer drug.[1][2][3]
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ECHA InfoCard | 100.257.446 |
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Formula | C10H12ClNO |
Molar mass | 197.66 g·mol−1 |
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Melting point | 198 °C (388 °F) |
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The exact pharmacology of 4-CMC is unknown, though it is probably a dopamine and serotonin releasing agent. Its chemical structure closely resembles para-chloromethamphetamine and studies involving mice indicate that it is neurotoxic.[4]
Clephedrone is an Anlage I controlled drug in Germany.
Sweden's public health agency suggested classifying 4-Chloromethcathinone (klefedron) as illegal narcotic on June 1, 2015.[5]
As of October 2015 4-CMC is a controlled substance in China.[6]
4-CMC is considered a Schedule 1 substance in Virginia.[7]
In December 2019, the UNODC announced scheduling recommendations placing 4-CMC into Schedule II.[8]