4C-T-2

Summary

2,5-Dimethoxy-4-ethylthio-α-ethylphenethylamine (4C-T-2) is a synthetic drug of the phenethylamine chemical class. It is the α-ethylated analogue of 2C-T-2.

4C-T-2
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • 1-[(2,5-dimethoxy-4-ethylthio)phenyl]butan-2-amine
CAS Number
PubChem CID
  • 11197523
ChemSpider
  • 9372592 checkY
UNII
  • AY9HDQ4A2H
ChEMBL
  • ChEMBL372719 checkY
Chemical and physical data
FormulaC14H23NO2S
Molar mass269.40 g·mol−1
3D model (JSmol)
  • Interactive image
  • COC1=C(CC(CC)N)C=C(OC)C(SCC)=C1
  • InChI=1S/C14H23NO2S/c1-5-11(15)7-10-8-13(17-4)14(18-6-2)9-12(10)16-3/h8-9,11H,5-7,15H2,1-4H3 checkY
  • Key:KLAWPCIXPDTGCZ-UHFFFAOYSA-N checkY
  (verify)

Pharmacology edit

Binding profile edit

4C-T-2 has affinity (Ki) for the 5-HT1A (5,339 nM), 5-HT1E (9,879 nM), 5-HT2A (274.1 nM), 5-HT2B (58.1 nM), 5-HT2C (468.6 nM), 5-HT5A (1,587 nM), 5-HT7 (3,829), D3 (1,273 nM), β2-adrenergic (124.9 nM), I1 (946.5 nM), and σ1 (514 nM) receptors.[1] The activity of 4C-T-2 at these sites has not been assayed, with the exception of the 5-HT2A and 5-HT2C receptors where it acts as a partial agonist.[1]

See also edit

References edit

  1. ^ a b Ray TS (February 2010). "Psychedelics and the human receptorome". PLOS ONE. 5 (2): e9019. Bibcode:2010PLoSO...5.9019R. doi:10.1371/journal.pone.0009019. PMC 2814854. PMID 20126400.