5,N,N-TMT

Summary

5,N,N-trimethyltryptamine (5,N,N-TMT; 5-TMT) is a tryptamine derivative that is a psychedelic drug. It was first made in 1958 by Edwin H. P. Young.[1] In animal experiments it was found to be in between DMT and 5-MeO-DMT in potency[2][3] which would suggest an active dosage for humans in the 20–60 mg range. Human psychoactivity for this compound has been claimed in reports on websites such as Erowid but has not been independently confirmed.

5,N,N-TMT
Identifiers
  • (2-(5-methyl-1H-indol-3-yl)-1-methyl-ethyl)dimethylamine
CAS Number
  • 22120-39-4 checkY
PubChem CID
  • 1837
ChemSpider
  • 1771 checkY
UNII
  • HIX0SK1CCX
CompTox Dashboard (EPA)
  • DTXSID30176641 Edit this at Wikidata
ECHA InfoCard100.164.424 Edit this at Wikidata
Chemical and physical data
FormulaC13H18N2
Molar mass202.301 g·mol−1
3D model (JSmol)
  • Interactive image
  • c1c(ccc2c1c(c[nH]2)CCN(C)C)C
  • InChI=1S/C13H18N2/c1-10-4-5-13-12(8-10)11(9-14-13)6-7-15(2)3/h4-5,8-9,14H,6-7H2,1-3H3 checkY
  • Key:NCGJLYBZSJSCIC-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Legal Status edit

United States edit

5,N,N-TMT is not scheduled at the federal level in the United States,[4][5] but it could be considered an analog of 5-MeO-DMT, in which case, sales or possession intended for human consumption could be prosecuted under the Federal Analog Act.

See also edit

References edit

  1. ^ Young EH (1958). "704. The synthesis of 5-hydroxytryptamine (serotonin) and related tryptamines". Journal of the Chemical Society (Resumed): 3493–6. doi:10.1039/JR9580003493.
  2. ^ Glennon RA, Gessner PK (April 1979). "Serotonin receptor binding affinities of tryptamine analogues". Journal of Medicinal Chemistry. 22 (4): 428–32. doi:10.1021/jm00190a014. PMID 430481.
  3. ^ Glennon RA, Young R, Rosecrans JA, Kallman MJ (1980). "Hallucinogenic agents as discriminative stimuli: a correlation with serotonin receptor affinities". Psychopharmacology. 68 (2): 155–8. doi:10.1007/BF00432133. PMID 6776558. S2CID 1674481.
  4. ^ "§ 1308.11 Schedule I." Archived from the original on 2009-08-27. Retrieved 2014-12-17.
  5. ^ "§ 1308.11 Schedule I." e-CFR. 2022-02-17. Archived from the original on 2022-02-10.