5-(Nonyloxy)tryptamine is a tryptamine derivative which acts as a selective agonist at the 5-HT1B receptor. Increasing the O-alkoxy chain length in this series gives generally increasing potency and selectivity for 5-HT1B, with highest activity found for the nonyloxy derivative, having a 5-HT1B binding affinity of 1.0 nM, and around 300-fold selectivity over the related 5-HT1A receptor.[1][2]
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Other names | 5-(Nonyloxy)-1H-indole-3-ethanamine |
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Formula | C19H30N2O |
Molar mass | 302.462 g·mol−1 |
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