5-Iodowillardiine is a selective agonist for the kainate receptor, with only limited effects at the AMPA receptor.[1] It is selective for kainate receptors composed of GluR5 subunits.[2][3] It is an excitotoxic neurotoxin in vivo,[4][5] but has proved highly useful for characterising the subtypes and function of the various kainate receptors in the brain and spinal cord.[6][7][8]
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IUPAC name
(2S)-2-Amino-3-(5-iodo-2,4-dioxopyrimidin-1-yl)propanoic acid
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Properties | |
C7H8IN3O4 | |
Molar mass | 325.061 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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