5F-ADBICA

Summary

5F-ADBICA (also known as 5F-ADB-PICA) is an indole-based synthetic cannabinoid that is a potent agonist at CB1 receptors and CB2 receptors with EC50 values of 0.77 nM and 1.2 nM respectively.[1][2]

5F-ADBICA
Legal status
Legal status
Identifiers
  • N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-1-(5-fluoropentyl)indole-3-carboxamide
CAS Number
  • 1801338-27-1
PubChem CID
  • 118796421
ChemSpider
  • 52085200
UNII
  • U9H280G9O7
Chemical and physical data
FormulaC20H28FN3O2
Molar mass361.461 g·mol−1
3D model (JSmol)
  • Interactive image
  • CC(C)(C)[C@@H](C(=O)N)NC(=O)C1=CN(C2=CC=CC=C21)CCCCCF
  • InChI=1S/C20H28FN3O2/c1-20(2,3)17(18(22)25)23-19(26)15-13-24(12-8-4-7-11-21)16-10-6-5-9-14(15)16/h5-6,9-10,13,17H,4,7-8,11-12H2,1-3H3,(H2,22,25)(H,23,26)/t17-/m1/s1
  • Key:ITZSOCZDFSHNCL-QGZVFWFLSA-N

Legal status edit

 
E-cigarette sample containing 5F-ADBICA from a patient at the Poison Control Center of Bach Mai Hospital

China edit

As of October 2015 5F-ADBICA is a controlled substance in China.[3]

See also edit

References edit

  1. ^ Banister SD, Moir M, Stuart J, Kevin RC, Wood KE, Longworth M, et al. (September 2015). "Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA". ACS Chemical Neuroscience. 6 (9): 1546–59. doi:10.1021/acschemneuro.5b00112. PMID 26134475.
  2. ^ "5F-ADBICA". Southern Association of Forensic Scientists. Retrieved 21 July 2015.
  3. ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.