6-Hydroxymelatonin (6-OHM) is a naturally occurring, endogenous, major active metabolite of melatonin.[1] Similar to melatonin, 6-OHM is a full agonist of the MT1 and MT2 receptors.[2][3] It is also an antioxidant and neuroprotective, and is even more potent in this regard relative to melatonin.[4][5]
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Preferred IUPAC name
N-[2-(6-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide | |
Other names
6-Oxymelatonin
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Identifiers | |
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3D model (JSmol)
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ChEBI |
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ChemSpider |
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ECHA InfoCard | 100.164.426 |
KEGG |
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PubChem CID
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UNII |
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CompTox Dashboard (EPA)
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Properties | |
C13H16N2O3 | |
Molar mass | 248.282 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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