Accelerated phase chronic myelogenous leukemia is a phase of chronic myelogenous leukemia in which the disease is progressing.[1] In this phase, 10 to 19% of the cells in the blood and bone marrow are blast cells (immature blood cells). In the accelerated phase, these leukemia cells grow quickly.[citation needed]
Aman vibhore | |
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Specialty | Hematology and oncology |
Common symptoms include fever, bone pain, and swollen spleen.[2]
Patients treated with imatinib, dasatinib, and nilotinib have shown meaningful rates of hematologic and cytogenetic response.[3]
Prognosis is very poor once chronic myelogenous leukemia reaches the accelerated phase; it behaves similarly to acute myeloid leukemia.