Acecarbromal (INN) (brand names Sedamyl, Abasin, Carbased, Paxarel, Sedacetyl, numerous others), also known as acetylcarbromal and acetyladalin, is a hypnotic and sedative drug of the ureide (acylurea) group discovered by Bayer in 1917[1] that was formerly marketed in the United States and Europe.[2][3] It is also used in combination with extract of quebracho and vitamin E as a treatment for erectile dysfunction under the brand name Afrodor in Europe.[4][5][6] Acecarbromal is structurally related to the barbiturates, which are basically cyclized ureas.[7] Prolonged use is not recommended as it can cause bromine poisoning.[7]
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Preferred IUPAC name
N-(Acetylcarbamoyl)-2-bromo-2-ethylbutanamide | |
Other names
1-Acetyl-3-(2-bromo-2-ethylbutyryl)urea
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Identifiers | |
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3D model (JSmol)
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ChemSpider |
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ECHA InfoCard | 100.000.953 |
EC Number |
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KEGG |
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MeSH | acecarbromal |
PubChem CID
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UNII |
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CompTox Dashboard (EPA)
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Properties | |
C9H15BrN2O3 | |
Molar mass | 279.134 g·mol−1 |
Pharmacology | |
Oral | |
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Related compounds
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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