Adafenoxate is a compound related to centrophenoxine, that has been found to act as a nootropic in rats.[1]
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Preferred IUPAC name
2-[(Adamantan-1-yl)amino]ethyl (4-chlorophenoxy)acetate | |
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CompTox Dashboard (EPA)
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Properties | |
C20H26ClNO3 | |
Molar mass | 363.87834 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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Ex 1: 4-Chlorophenoxyacetic acid (pCPA) [122-88-3] is converted to its acid chloride to give 4-chlorophenoxyacetyl chloride [4122-68-3] (1). Esterification with 2-(1-adamantylamino)ethanol [3716-66-3] (2) gives Adafenoxate (3) in a single step.
Ex 2: Same as above but Fischer–Speier esterification done via a DS-trap. This gives an 88% yield.