Adafenoxate is a compound related to centrophenoxine, that has been found to act as a nootropic in rats.[1]
Names | |
---|---|
Preferred IUPAC name
2-[(Adamantan-1-yl)amino]ethyl (4-chlorophenoxy)acetate | |
Identifiers | |
| |
3D model (JSmol)
|
|
ChEMBL |
|
ChemSpider |
|
PubChem CID
|
|
UNII |
|
CompTox Dashboard (EPA)
|
|
| |
| |
Properties | |
C20H26ClNO3 | |
Molar mass | 363.88 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
verify (what is ?)
Infobox references
|
Adafenoxate can be prepared starting with 4-chlorophenoxyacetic acid (pCPA) by converting it to its acid chloride to give 4-chlorophenoxyacetyl chloride (1).[2] Esterification with 2-(1-adamantylamino)ethanol (2) gives adafenoxate (3).
Alternatives, the final step can be accomplished via Fischer–Speier esterification using a Dean-Stark trap.