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Adipiodone

Summary

Adipiodone (INN, or iodipamide; trade names Cholografin and Biligrafin) is a pharmaceutical drug used as a radiocontrast agent in X-ray imaging. It was introduced in the 1950s.[1][2]

Adipiodone
Clinical data
Trade namesCholografin, Biligrafin
Other names3-[[6-[(3-Carboxy-2,4,6-triiodophenyl)amino]-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 3-{5-[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]pentanamido}-2,4,6-triiodobenzoic acid
CAS Number
  • 606-17-7 checkY
PubChem CID
  • 3739
IUPHAR/BPS
  • 7400
DrugBank
  • DB04711 checkY
ChemSpider
  • 3608 checkY
UNII
  • TKQ858A3VW
KEGG
  • D01774 checkY
ChEBI
  • CHEBI:31176
ChEMBL
  • ChEMBL1165268 checkY
CompTox Dashboard (EPA)
  • DTXSID6023153 Edit this at Wikidata
ECHA InfoCard100.009.187 Edit this at Wikidata
Chemical and physical data
FormulaC20H14I6N2O6
Molar mass1139.767 g·mol−1
3D model (JSmol)
  • Interactive image
  • O=C(Nc1c(I)c(c(I)cc1I)C(=O)O)CCCCC(=O)Nc2c(I)c(C(=O)O)c(I)cc2I
  • InChI=1S/C20H14I6N2O6/c21-7-5-9(23)17(15(25)13(7)19(31)32)27-11(29)3-1-2-4-12(30)28-18-10(24)6-8(22)14(16(18)26)20(33)34/h5-6H,1-4H2,(H,27,29)(H,28,30)(H,31,32)(H,33,34) checkY
  • Key:FFINMCNLQNTKLU-UHFFFAOYSA-N checkY
  (verify)

References edit

  1. ^ Hastings-James R, Glazebrook AJ (April 1955). "Cholografin". Canadian Medical Association Journal. 72 (8): 561–5. PMC 1825662. PMID 14364399.
  2. ^ Dilger SK, Nelson N, Venkatesh SK, Ehman EC, Fidler JL, Fletcher JG, et al. (September 2019). "Computed Tomography Cholangiography Using the Magnetic Resonance Contrast Agent Gadoxetate Disodium: A Phantom Study". Investigative Radiology. 54 (9): 572–579. doi:10.1097/RLI.0000000000000580. PMID 31261292. S2CID 195772743.