Alcohol sulfotransferase

Summary

Alcohol sulfotransferase is an enzyme that catalyzes the sulfate conjugation of primary and secondary alcohols including many hormones, neurotransmitters, drugs, and xenobiotic compounds.[1][2]

Alcohol sulfotransferase
Identifiers
EC no.2.8.2.2
CAS no.9032-76-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

The chemical reaction is:

an alcohol + 3'-phosphoadenylyl-sulfate adenosine 3',5'-bisphosphate + an organosulfate + H+

Family members edit

Human genes that encode alcohol sulfotransferases include:

See also edit

References edit

  1. ^ Lyon ES, Jakoby WB (July 1980). "The identity of alcohol sulfotransferases with hydroxysteroid sulfotransferases". Arch. Biochem. Biophys. 202 (2): 474–81. doi:10.1016/0003-9861(80)90452-X. PMID 6935986.
  2. ^ Lyon ES, Marcus CJ, Wang JL, Jakoby WB (1981). "Hydroxysteroid sulfotransferase". Meth. Enzymol. 77: 206–13. doi:10.1016/S0076-6879(81)77027-7. PMID 6173569.

External links edit