Alfaprostol

Summary

Alfaprostol is a bioactive analog of prostaglandin F. Alfaprostol is a luteolytic agent used injectably for scheduling of estrus in mares for purposes of planned breeding. It is also used for treating of postweaning anestrus in economically important farm animals. For these purposes, alfaprostol is more potent than naturally occurring prostaglandin F.

Alfaprostol
Identifiers
  • 74176-31-1 checkY
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL2104662
ChemSpider
  • 5293021
ECHA InfoCard 100.070.657 Edit this at Wikidata
  • 6436172
UNII
  • 4XKL2JJ08I checkY
  • InChI=1S/C24H38O5/c1-29-24(28)12-8-3-2-7-11-20-21(23(27)17-22(20)26)16-15-19(25)14-13-18-9-5-4-6-10-18/h2,7,18-23,25-27H,3-6,8-14,17H2,1H3/b7-2-/t19-,20+,21+,22-,23+/m0/s1
    Key: OZDSQCVLNUIYLN-JNAAKWLTSA-N
  • COC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1C#C[C@H](CCC2CCCCC2)O)O)O
Properties
C24H38O5
Molar mass 406.56 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References edit

  • Boiti, C; Canali, C; Zerani, M; Gobbetti, A (1998). "Changes in refractoriness of rabbit corpora lutea to a prostaglandin F2 alpha analogue, alfaprostol, during pseudopregnancy". Prostaglandins & Other Lipid Mediators. 56 (4): 255–64. doi:10.1016/s0090-6980(98)00053-7. PMID 9777657.