Born in Worthington, Massachusetts, Stone attended the common schools. He married Anna Townsend of Buffalo, New York. In 1832, he moved to Columbus, Ohio, and engaged in mercantile pursuits.

Stone was elected as a Democrat to the Twenty-eighth Congress to fill the vacancy caused by the death of Heman A. Moore and served from October 8, 1844, to March 3, 1845. He was not a candidate for renomination. He was appointed Ohio State Treasurer by Governor Salmon P. Chase in 1857 to fill the vacancy caused by the resignation of William H. Gibson. He was elected and reelected to the same office as a Republican^[1] and served until 1862. He was appointed as collector of internal revenue for the Columbus district of Ohio in 1862 and served until his death in Columbus, Ohio, August 2, 1865. Stone was found dead at the graves of his two children at Green Lawn Cemetery.^[2] He was interred in Green Lawn Cemetery. In 1888 his remains were removed to Forest Lawn Cemetery in Buffalo, New York.

• Smith, Joseph P, ed. (1898). History of the Republican Party in Ohio. Vol. I. Chicago: the Lewis Publishing Company.

• United States Congress. "Alfred P. Stone (id: S000952)". Biographical Directory of the United States Congress.

  This article incorporates public domain material from the Biographical Directory of the United States Congress