Wilks, Billie, and Bueller are the last survivors of a devastating assault on the aliens' home planet. They are again refugees when they return to the Solar System, fleeing Earth's Alien infestation in a military transport that hurtles them through unknown space and an unknown destination.

They are unaware that the remote colony and military outpost they will approach is at the mercy of a general named Spears with an agenda all his own. Now Billie, Wilks, and Bueller face a new nightmare, and it is nothing they could ever have imagined: a gift of madness from an alien world, an unbalanced mind and the experiences of a mysterious pilot named Lieutenant Ellen Ripley.