Andrew Neil James McKenzie FRS FMedSci[2] is a molecular biologist and group leader in the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB).[3]
Andrew McKenzie | |
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Born | Andrew Neil James McKenzie |
Education | University of London (PhD) |
Spouse | Sarah Bell |
Children | James Mckenzie, Ross Mckenzie |
Scientific career | |
Fields | Immunology Autoimmunity Molecular biology |
Institutions | Laboratory of Molecular Biology University of Cambridge National Institute for Medical Research[1] |
Thesis | Cellular and humoral aspects of the immune response of the larval stages of Calliphora vomitoria L. (Insecta: Diptera) (1988) |
Website | www2 |
McKenzie was educated at the University of London where he was awarded a PhD for research on the immune response of the bluebottle fly (Calliphora vomitoria),[4] covering both humoral immunity and cell-mediated immunity.
McKenzie's research investigates how the innate immune system and adaptive immune system protect the body from infection, but can also lead to inflammation and pathology.[2] He has defined and characterised how biological networks orchestrate responses to pathogens and how dysregulation of these biological pathways can lead to diseases such as asthma and allergy.[2][5]
His identification of the cytokine Interleukin 13 and the subsequent unearthing of its central role in allergic asthma led to his discovery of type-2 innate lymphoid cells (ILC2).[6][7] These cells secrete large quantities of cytokines and represent a new druggable biological target for intervention in inflammation and infection.[2]
McKenzie was elected a Fellow of the Royal Society (FRS) in 2017[2] and a Fellow of the Academy of Medical Sciences (FMedSci) in 2011.[8]
“All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --"Terms, conditions and policies | Royal Society". Archived from the original on 2016-11-11. Retrieved 2017-08-18.
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