Antistes (from Latin ante "before" and sto "stand") was from the sixteenth to the nineteenth century the title of the head of a church in the Reformed Churches in Switzerland. It was the highest office in churches with synodal church governance.

The word was used first in 1525 as an unofficial title of honor for Huldrych Zwingli in Zürich, then in 1530 for Johannes Oecolampadius in Basel and in 1532 for Heinrich Bullinger in Zürich.

The antistes was elected by the great council (the parliament) of the city and also held besides this office a pastorship of one of the main churches.

The antistes had to be an ordained minister. He was the official representative of the church. He presided over the synod, and over the theological examinations of candidates for the office of pastor. His direct rights were very limited, but a man with high leadership capabilities like Zwingli or Bullinger could exert a great influence on the church in this office.

In the late nineteenth century the title was replaced by other office designations, e.g. church president or president of the church council.

Antistites were an early form of bishops, and were also recorded in records about the Bona Dea Temple of the late Roman Republic and pre-Christian early Roman Empire.