Artesunate/amodiaquine, sold under the trade name Camoquin among others, is a medication used for the treatment of malaria.[3][4] It is a fixed-dose combination of artesunate and amodiaquine.[3] Specifically it recommended for acute uncomplicated Plasmodium falciparum malaria.[5] It is taken by mouth.[4]
Combination of | |
---|---|
Artesunate | Antimalarial |
Amodiaquine | Antimalarial |
Clinical data | |
Trade names | Camoquin, others[1] |
Other names | ASAQ |
ATC code |
|
Identifiers | |
CAS Number |
|
ChemSpider |
|
UNII |
|
(what is this?) (verify) |
Common side effects include loss of appetite, nausea, abdominal pain, sleepiness, trouble sleeping, and cough.[6] Safety in pregnancy is not clear; however, the medication may be used if others are not possible.[6] It is believed to be safe for use during breastfeeding.[6] Artesunate and amodiaquine are both antimalarial medication; however, work by different mechanisms.[6]
Artesunate/amodiaquine was commercially launched in 2007.[7] It is on the World Health Organization's List of Essential Medicines.[3] Artesunate/amodiaquine is available as a generic medication.[7] As of 2014 it is not commercially available in the United States or United Kingdom.[1][8]
Early clinical trials showed that a once-a-day dosage was effective.[9] It was subsequently clinically shown to be equally effective as artemether/lumefantrine,[10] although it is likely to be more effective in the field due to its simpler once-a-day dosage compared to artemether/lumefantrine twice-per-day dosage.
Artesunate/amodiaquine was commercially launched in 2007 as an affordable treatment for malaria, devised by DNDi in partnership with Sanofi-Aventis.[7] ASAQ was handed over to the MMV Access and Product Management Team in May 2015.[11]