Atamestane (developmental code name SH-489), also known as metandroden, as well as 1-methylandrosta-1,4-diene-3,17-dione, is a steroidal aromatase inhibitor that was studied in the treatment of cancer.[2] It blocks the production of estrogen in the body. The drug is selective, competitive, and irreversible in its inhibition of aromatase.[3][additional citation(s) needed]
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Other names | SH-489; Metandroden; 1-Methylandrosta-1,4-diene-3,17-dione |
Routes of administration | By mouth[1] |
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Formula | C20H26O2 |
Molar mass | 298.426 g·mol−1 |
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This article incorporates public domain material from Dictionary of Cancer Terms. U.S. National Cancer Institute.