BRL-54443

Summary

BRL-54443 is a drug which acts as a selective agonist for the 5-HT1E and 5-HT1F serotonin receptor subtypes.[1][2]

BRL-54443
Identifiers
  • 3-(1-methylpiperidin-4-yl)-1H-indol-5-ol
CAS Number
  • 57477-39-1 checkY
PubChem CID
  • 2438
IUPHAR/BPS
  • 3927
ChemSpider
  • 2344 ☒N
UNII
  • Q2DH1CHI0Y
CompTox Dashboard (EPA)
  • DTXSID40206089 Edit this at Wikidata
Chemical and physical data
FormulaC14H18N2O
Molar mass230.311 g·mol−1
3D model (JSmol)
  • Interactive image
  • Oc3ccc1c(c(c[nH]1)C2CCN(C)CC2)c3
  • InChI=1S/C14H18N2O/c1-16-6-4-10(5-7-16)13-9-15-14-3-2-11(17)8-12(13)14/h2-3,8-10,15,17H,4-7H2,1H3 ☒N
  • Key:WKNFADCGOAHBPG-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

References edit

  1. ^ McKune CM, Watts SW (April 2001). "Characterization of the serotonin receptor mediating contraction in the mouse thoracic aorta and signal pathway coupling". The Journal of Pharmacology and Experimental Therapeutics. 297 (1): 88–95. PMID 11259531.
  2. ^ Janssen P, Tack J, Sifrim D, Meulemans AL, Lefebvre RA (May 2004). "Influence of 5-HT1 receptor agonists on feline stomach relaxation". European Journal of Pharmacology. 492 (2–3): 259–67. doi:10.1016/j.ejphar.2004.03.054. PMID 15178373.