CFU-Meg is a colony forming unit. Haematopoiesis in the bone marrow starts off from a haematopoietic stem cell (HSC) and this can differentiate into the myeloid and lymphoid cell lineages. In order to eventually produce a megakaryocyte, the haematopoietic stem cell must generate myeloid cells, so it becomes a common myeloid progenitor, CFU-GEMM. This in turn develops into CFU-Meg, which is the colony forming unit that leads to the production of megakaryocytes.[1][2][3]
CFU-Meg | |
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Details | |
Gives rise to | Megakaryocytes and those to platelets |
Location | Bone marrow |
Function | Colony forming unit |
Identifiers | |
TH | H2.00.04.3.02013 |
Anatomical terms of microanatomy [edit on Wikidata] |
Some sources prefer the term "CFU-Mega".[4]