The Cyp11c1 is a fish gene encoding a CYP450 enzyme, which was originally found in Zebrafish (Danio rerio), this enzyme mainly catalyze the formation of cortisol and 11-Ketotestosterone (11-KT).[1] 11-KT is the endogenous androgen in zebrafish.[2] CYP11C is the orthologous to CYP11B, tetrapod's CYP11B1 evolved from CYP11C1 of fish, and CYP11B/11C are the ohonologues to CYP11A, which duplicated during 2R event.[3]
cytochrome P450, family 11, subfamily c, polypeptide 1 | |||||||
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Identifiers | |||||||
Organism | |||||||
Symbol | CYP11C1 | ||||||
Entrez | 791124 | ||||||
HomoloGene | 128035 | ||||||
RefSeq (mRNA) | NM_001080204.1 | ||||||
RefSeq (Prot) | NP_001073673.1 | ||||||
UniProt | A1XRK1 | ||||||
Other data | |||||||
EC number | 1.14.15.4 | ||||||
Chromosome | 16: 54.46 - 54.48 Mb | ||||||
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