Cane River Lake (French: Lac de la rivière aux Cannes) is a 35 mi (56 km) oxbow lake formed from a portion of the Red River in Natchitoches Parish, Louisiana, United States. It runs throughout the Natchitoches' historic district to the south and is famous for the numerous plantations, particularly Melrose being located on or near its banks.

Cane River Lake
Cane River Lake near Melrose Plantation in south Natchitoches Parish
Cane River Lake Show map of Louisiana Cane River Lake Show map of the United States
Location	Natchitoches Parish, Louisiana
Coordinates	31°38′10.74″N 93°0′13.96″W / 31.6363167°N 93.0038778°W / 31.6363167; -93.0038778
Type	oxbow lake
Basin countries	United States
Max. length	c. 35 mi (56 km)
Max. width	100 ft (30 m)
Average depth	8 ft (2.4 m)
Max. depth	15 ft (4.6 m)
Settlements	Natchitoches, Natchez, Bermuda, Melrose

The lake was widely publicized between 1966 and 1979 by the nationally known outdoorsman Grits Gresham, host (with Curt Gowdy) of ABC's The American Sportsman and author of numerous books and columns on hunting, fishing, and guns.

The American historian, Henry C. Dethloff, grew up on Cane River and as a youth swam the entire width of the stream underwater.^[1]