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Catherine Dulac

Summary

Catherine Dulac is a French–American biologist.[2] She is the Higgins Professor in Molecular and Cellular Biology at Harvard University, where she served as department chair from 2007 to 2013.[3] She is also an investigator at the Howard Hughes Medical Institute. She was born in 1963 in France. She came to the United States for her postdoctoral study in 1991.

Catherine Dulac
Born1963[1]
Alma materUniversity of Paris
Known forMammalian pheromones
AwardsRichard Lounsbery Award Breakthrough Prize in Life Sciences
Scientific career
Academic advisorsRichard Axel

Dulac has done extensive research on the molecular biology of olfactory signaling in mammals, particularly including pheromones,[4] and downstream brain circuits controlling sex-specific behaviors.[5] She developed a novel screening strategy based on screening cDNA libraries from single neurons and a new method of cloning genes from single neurons. As a postdoc, Dulac discovered the first family of mammalian pheromone receptors when working in Nobel laureate Richard Axel's laboratory at Columbia University.[6]

Biography edit

Dulac grew up in Montpellier, France, graduated from the École Normale Supérieure de la rue d'Ulm, Paris, and earned a Ph.D. in developmental biology from the University of Paris in 1991.[1] She worked with Nicole Le Douarin on developmental biology, and carried out her postdoc studies with Richard Axel at Columbia University where she identified the first genes encoding mammalian pheromone receptors.

Dulac joined the faculty of Harvard Molecular and Cell Biology in 1996,[7] She was promoted to associate professor in 2000 and full professor in 2001. She is currently an investigator at the Howard Hughes Medical Institute and was the Chair of Harvard's Department of Molecular and Cellular Biology[1] until 2013. She teaches three graduate level course including Molecular Basis of Behavior, Molecular and Cellular Biology of the Senses and Their Disorders, and Molecular and Developmental Biology Neurobiology.

Publications edit

Notable papers edit

  • Wu, Zheng; Autry, Anita E.; Bergan, Joseph F.; Watabe-Uchida, Mitsuko; Dulac, Catherine G. (2014). "Galanin neurons in the medial preoptic area govern parental behaviour". Nature. 509 (7500). Springer Science and Business Media LLC: 325–330. Bibcode:2014Natur.509..325W. doi:10.1038/nature13307. ISSN 0028-0836. PMC 4105201. PMID 24828191.
  • Bergan, Joseph F; Ben-Shaul, Yoram; Dulac, Catherine (June 3, 2014). "Sex-specific processing of social cues in the medial amygdala". eLife. 3. eLife Sciences Publications, Ltd: e02743. doi:10.7554/elife.02743. ISSN 2050-084X. PMC 4038839. PMID 24894465.
  • Gregg, C.; Zhang, J.; Butler, J. E.; Haig, D.; Dulac, C. (July 8, 2010). "Sex-Specific Parent-of-Origin Allelic Expression in the Mouse Brain". Science. 329 (5992). American Association for the Advancement of Science (AAAS): 682–685. Bibcode:2010Sci...329..682G. doi:10.1126/science.1190831. ISSN 0036-8075. PMC 2997643. PMID 20616234.
  • Kimchi, Tali; Xu, Jennings; Dulac, Catherine (2007). "A functional circuit underlying male sexual behaviour in the female mouse brain". Nature. 448 (7157). Springer Science and Business Media LLC: 1009–1014. Bibcode:2007Natur.448.1009K. doi:10.1038/nature06089. ISSN 0028-0836. PMID 17676034. S2CID 4427883.
  • Tietjen, Ian; Rihel, Jason M.; Cao, Yanxiang; Koentges, Georgy; Zakhary, Lisa; Dulac, Catherine (2003). "Single-Cell Transcriptional Analysis of Neuronal Progenitors". Neuron. 38 (2). Elsevier BV: 161–175. doi:10.1016/s0896-6273(03)00229-0. ISSN 0896-6273. PMID 12718852. S2CID 5872628.
  • Pantages, Erica; Dulac, Catherine (2000). "A Novel Family of Candidate Pheromone Receptors in Mammals". Neuron. 28 (3). Elsevier BV: 835–845. doi:10.1016/s0896-6273(00)00157-4. ISSN 0896-6273. PMID 11163270. S2CID 15023062.
  • Liman, E. R.; Corey, D. P.; Dulac, C. (May 11, 1999). "TRP2: A candidate transduction channel for mammalian pheromone sensory signaling". Proceedings of the National Academy of Sciences. 96 (10): 5791–5796. Bibcode:1999PNAS...96.5791L. doi:10.1073/pnas.96.10.5791. ISSN 0027-8424. PMC 21939. PMID 10318963.
  • Belluscio, Leonardo; Koentges, Georgy; Axel, Richard; Dulac, Catherine (1999). "A Map of Pheromone Receptor Activation in the Mammalian Brain". Cell. 97 (2). Elsevier BV: 209–220. doi:10.1016/s0092-8674(00)80731-x. ISSN 0092-8674. PMID 10219242. S2CID 18385498.
  • Dulac, Catherine; Axel, Richard (1995). "A novel family of genes encoding putative pheromone receptors in mammals". Cell. 83 (2). Elsevier BV: 195–206. doi:10.1016/0092-8674(95)90161-2. ISSN 0092-8674. PMID 7585937. S2CID 18784638.

Other edit

  • Dulac, Catherine (2005). "Sex and the Single Splice". Cell. 121 (5). Elsevier BV: 664–666. doi:10.1016/j.cell.2005.05.017. ISSN 0092-8674. PMID 15935752. S2CID 15137565.
  • "Sensory systems". Current Opinion in Neurobiology. 14 (4). Elsevier BV: 403–406. 2004. doi:10.1016/j.conb.2004.07.010. ISSN 0959-4388. S2CID 54341126.
  • Dulac, Catherine; Torello, A. Thomas (2003). "Molecular detection of pheromone signals in mammals: from genes to behaviour". Nature Reviews Neuroscience. 4 (7). Springer Science and Business Media LLC: 551–562. doi:10.1038/nrn1140. ISSN 1471-003X. PMID 12838330. S2CID 11120696.
  • Dulac, Catherine (2000). "The Physiology of Taste, Vintage 2000". Cell. 100 (6). Elsevier BV: 607–610. doi:10.1016/s0092-8674(00)80697-2. ISSN 0092-8674. PMID 10761926. S2CID 7721853.

Awards and honors edit

She was elected a Member of the American Philosophical Society in 2019.[11]

References edit

  1. ^ a b c d e f g h [1]. academie-sciences.fr
  2. ^ "Harvard scientist Catherine Dulac awarded for work on parenting instinct". RFI. September 14, 2020. Retrieved September 15, 2020.
  3. ^ "McGovern Institute awards 2017 Scolnick Prize to Catherine Dulac". MIT News. Retrieved February 3, 2018.
  4. ^ Gitschier, J. (2011). "Vive La Différence: An Interview with Catherine Dulac". PLOS Genetics. 7 (6): e1002140. doi:10.1371/journal.pgen.1002140. PMC 3121755. PMID 21731502.
  5. ^ "McGovern Institute awards 2017 Scolnick Prize to Catherine Dulac". MIT News. Retrieved February 3, 2018.
  6. ^ "Catherine Dulac". Harvard University. Archived from the original on June 15, 2011. Retrieved June 15, 2011.
  7. ^ "Harvard Portrait: Catherine Dulac", Harvard Magazine, Sept. – Oct. 2005.
  8. ^ Hastings, J. W. (May 12, 2004) "Catherine Dulac Elected to Membership in the American Academy of Arts and Sciences" Archived 2016-11-15 at the Wayback Machine, Harvard University MCB News.
  9. ^ "Dulac Receives Award from Society for Neuroscience". Harvard University – Department of Molecular & Cellular Biology. October 19, 2019. Retrieved September 10, 2020.
  10. ^ Knapp, Alex. "2021 Breakthrough Prize Winners Announced: Researcher Who Developed Protein Design Technology Awarded $3 Million". Forbes. Retrieved September 10, 2020.
  11. ^ "Catherine Dulac Elected to American Philosophical Society". Harvard University – Department of Molecular & Cellular Biology. June 13, 2019. Retrieved September 10, 2020.

External links edit

 
Wikimedia Commons has media related to Catherine Dulac.
  • Research Summary & Profile, Harvard University
  • HHMI profile Archived 2013-05-11 at the Wayback Machine
  • "Pheromones Control Gender Recognition in Mice", January 31, 2002 (HHMI Research News)
  • "Harvard Portrait: Catherine Dulac",
  • "Making the Paper: Catherine Dulac", Nature, v.448 (August 30, 2007).
  • Catherine Dulac Seminars

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