Central Jacob Lines (Urdu: جیکب لاین) is a neighborhood in Karachi East district of Karachi, Pakistan. It was previously administered as part of Jamshed Town,^[1] which was disbanded In 2011. It is named after General John Jacob.

There are several ethnic groups in Central Jacob Lines including Muhajirs, Punjabis, Sindhis, Kashmiris, Seraikis, Pakhtuns, Balochis, Memons, Bohras, Ismailis, etc.