2-Chloro-5-hydroxyphenylglycine or CHPG is an agonist of the metabotropic glutamate receptors, specific for mGluR5.[1]
Names | |
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IUPAC name
Amino(2-chloro-5-hydroxyphenyl)acetic acid
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Identifiers | |
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3D model (JSmol)
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Abbreviations | CHPG |
ChemSpider |
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ECHA InfoCard | 100.162.133 |
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PubChem CID
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UNII |
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CompTox Dashboard (EPA)
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Properties | |
C8H6ClNO3 | |
Molar mass | 199.59 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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It is capable of directly potentiating the depolarization of hippocampal CA1 neurons induced through NMDA administration.[2]