Christopher Simpson may refer to:

• Christopher Simpson (musician) (c. 1602/06–1669), English musician and composer
• Christopher Simpson (actor) (born 1975), Irish actor
• Christopher Simpson (cricketer) (1890–?), Guyanese cricketer
• Chris Patrick-Simpson (born 1979), Northern Irish actor
• Chris Simpson (cardiologist) (born 1967), Canadian cardiologist
• Chris Simpson (cricketer) (born 1982), Australian cricketer
• Chris Simpson (squash player) (born 1987), British squash player
• Chris Simpson (musician), musician with the band Magna Carta