Demoxepam

Summary

Demoxepam[1] is a drug which is a benzodiazepine derivative. It is a metabolite of chlordiazepoxide[2] and has anticonvulsant properties[3][4] and presumably other characteristic benzodiazepine properties.

Demoxepam
Pharmacokinetic data
Elimination half-life35–40 hours
Identifiers
  • 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one-4-oxide
CAS Number
  • 963-39-3 ☒N
PubChem CID
  • 13756
ChemSpider
  • 10441314 checkY
UNII
  • 8X1XP5M0SB
KEGG
  • D02600 checkY
ChEMBL
  • ChEMBL1597677 ☒N
CompTox Dashboard (EPA)
  • DTXSID4046155 Edit this at Wikidata
ECHA InfoCard100.012.287 Edit this at Wikidata
Chemical and physical data
FormulaC15H11ClN2O2
Molar mass286.71 g·mol−1
3D model (JSmol)
  • Interactive image
  • ClC1=CC2=C(NC(C[N+]([O-])=C2C3=CC=CC=C3)=O)C=C1
  • InChI=1S/C15H11ClN2O2/c16-11-6-7-13-12(8-11)15(10-4-2-1-3-5-10)18(20)9-14(19)17-13/h1-8H,9H2,(H,17,19) checkY
  • Key:GGRWZBVSUZZMKS-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

See also edit

References edit

  1. ^ US Patent 3136815
  2. ^ Greenblatt DJ, Shader RI, MacLeod SM, Sellers EM (1978). "Clinical pharmacokinetics of chlordiazepoxide". Clinical Pharmacokinetics. 3 (5): 381–94. doi:10.2165/00003088-197803050-00004. PMID 359214.
  3. ^ "nortetrazepam". psychotropics.dk. 2003. Retrieved 7 December 2009.
  4. ^ "LIST OF INTERNATIONAL NON-PROPRIETARY NAMES (INNS), PROVIDED FOR PHARMACEUTICAL SUBSTANCES BY THE WORLD HEALTH ORGANIZATION, WHICH ARE FREE OF DUTY" (PDF). Official Journal of the European Communities. eur-lex.europa.eu. 23 October 2001. Retrieved 7 December 2009.