Dicyclohexylurea is an organic compound, specifically, a urea. It is the byproduct of the reaction of dicyclohexylcarbodiimide with amines or alcohols. It may be prepared by the reaction of cyclohexylamine and S,S-dimethyl dithiocarbonate.[1] 1,3-Dicyclohexyl urea (DCU) is a potent soluble epoxide hydrolase (sEH) inhibitor. It has been shown to lower systemic blood pressure by 22 ± 4 mmHg in SHR.[2]
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Preferred IUPAC name
N,N′-Dicyclohexylurea | |
Other names
DCU
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3D model (JSmol)
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ECHA InfoCard | 100.017.468 |
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CompTox Dashboard (EPA)
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Properties | |
C13H24N2O | |
Molar mass | 224.348 g·mol−1 |
Melting point | 230 to 233 °C (446 to 451 °F; 503 to 506 K) |
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H302 | |
P264, P270, P301+P312, P330, P501 | |
Safety data sheet (SDS) | External MSDS |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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