Distearoylphosphatidylcholine is a phosphatidylcholine, a kind of phospholipid. It is a natural constituent of cell membranes, eg. soybean phosphatidylcholines are mostly different 18-carbon phosphatidylcholines (including minority of saturated DSPC), and their hydrogenation results in 85% DSPC.[1] It can be used to prepare lipid nanoparticles which are used in mRNA vaccines,[2][3] In particular, it forms part of the drug delivery system for the Moderna and Pfizer COVID-19 vaccines.[4][5]
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Systematic IUPAC name
(2R)-2,3-Bis(octadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate | |
Other names
1,2-distearoyl-sn-glycero-3-phosphocholine, DSPC, 18:0 PC
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Identifiers | |
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3D model (JSmol)
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ChEBI |
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ChemSpider |
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ECHA InfoCard | 100.011.309 |
EC Number |
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PubChem CID
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UNII |
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CompTox Dashboard (EPA)
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Properties | |
C44H88NO8P | |
Molar mass | 790.161 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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