Twenty years after the events in the first Django, the title character has left the violent life of a gunslinger to become a monk. Living in seclusion in a monastery, he wants no more of the violent actions he perpetrated. Suddenly, he learns from a dying former lover that some time ago he had a young daughter, who has been kidnapped along with other children who are now working for a ruthless Belgian criminal known as El Diablo (The Devil) Orlowsky, who is an arms dealer and slave trader. The children and other prisoners work in Orlowsky's mine, from which he hopes to get rich from the spoils. Determined to find his daughter and nail the bad guys, Django gets some arms and goes on the warpath against Orlowsky's private army.

Django Strikes Again was conceived concurrently with Duccio Tessari's Tex and the Lord of the Deep; both projects were intended to represent a revival of the Spaghetti Western genre. Following the commercial failure of Tex, Sergio Corbucci, who had co-written Django Strikes Again and had initially agreed to direct it, refused to partake in its production.^[2] Shot on location in Colombia, the film represents the final screen appearance of Christopher Connelly, who died of cancer a year after its release.^[2] Nero stated in a 2012 interview that he is "not happy with the film" and called it "a bit flat".^[3]

Django Strikes Again was released theatrically in Germany on November 6, 1987 as Djangos Rückkehr.^[4]

Following a 2014 attempt to mount the project,^[5] it was reported in May 2016 that Franco Nero would reprise his role in a third and final outing as the titular character, entitled Django Lives! The film was to be set 50 years after the events of the original installment. John Sayles was to direct.^[6][7][8]

• Django Strikes Again at IMDb