Donatello was an Italian Renaissance sculptor

Donatello may refer to:

• Donatello Brown (born 1991), American football player
• Donatello (Teenage Mutant Ninja Turtles), a fictional character in the Teenage Mutant Ninja Turtles series
• Donatello (singer), an Italian singer
• Donatello Stefanucci (1896–1987), Italian painter
• Carmine Crocco (1830–1905), also known as Donatello, an Italian brigand
• Donatello, one of the three Multi-Purpose Logistics Modules.
• David di Donatello, the Italian film award