Dropropizine

Summary

Dropropizine (or dipropizine) is a cough suppressant[1] that is sold in Germany, Central America, South America, and some African countries such as Congo. It is sold as suppositories, tablets, and syrup. It is used to stop a cough caused by allergies or a cold.[2]

Dropropizine
Clinical data
Trade namesCatabex, Drobex, Kalmobex, Ribex, Teletux, Troferit, Tusofren
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • (RS)-3-(4-Phenylpiperazin-1-yl)propane-1,2-diol
CAS Number
  • 17692-31-8
PubChem CID
  • 3169
ChemSpider
  • 3057 checkY
UNII
  • U0K8WHL37U
KEGG
  • D07393 checkY
ChEMBL
  • ChEMBL151445 checkY
CompTox Dashboard (EPA)
  • DTXSID0045624 Edit this at Wikidata
ECHA InfoCard100.037.878 Edit this at Wikidata
Chemical and physical data
FormulaC13H20N2O2
Molar mass236.315 g·mol−1
3D model (JSmol)
  • Interactive image
  • OC(CN2CCN(c1ccccc1)CC2)CO
  • InChI=1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2 checkY
  • Key:PTVWPYVOOKLBCG-UHFFFAOYSA-N checkY
  (verify)

Side effects edit

Adverse effects include drowsiness, nausea, heartburn, and respiratory depression.[2]

See also edit

References edit

  1. ^ De Blasio F, Dicpinigaitis PV, Rubin BK, De Danieli G, Lanata L, Zanasi A (January 2012). "An observational study on cough in children: epidemiology, impact on quality of sleep and treatment outcome". Cough. 8 (1): 1. doi:10.1186/1745-9974-8-1. PMC 3274450. PMID 22269875.
  2. ^ a b Schlesser JL (1991). Drugs Available Abroad, 1st Edition. Derwent Publications Ltd. p. 71. ISBN 0-8103-7177-4.