Edward Hoyte Lyons (May 12, 1923 – January 25, 2009), nicknamed "Mouse", was a Major League Baseball second baseman who played for the Washington Senators in 1947.

Born in Winston-Salem, North Carolina, Lyons signed a contract out of Richard J. Reynolds High School with the Washington Senators when he was 17.^[1] While in the minor leagues, his baseball career was interrupted by World War II when he joined the United States Navy.^[1] He made his Major League debut with the Washington Senators in 1947. He played 7 games at second base and hit .154 in his only season in the Major Leagues. When his playing career ended he became a manager for the Senators, Red Sox, and Cardinals organizations.^[1] His coaching career came to an end after a leg injury and he served as a scout, ending with the Chicago Cubs in 1995.^[1] He was inducted into the Winston-Salem Baseball Hall of Fame in 1998.^[1] After his retirement, he resided in Clemmons, North Carolina and died on January 25, 2009, in Winston-Salem.^[1]