Edmund Henry Pendleton (1788 – February 25, 1862) was a U.S. Representative from New York.

Born in Savannah, Georgia, Pendleton received a liberal schooling as a youth. He graduated from Columbia College in 1805, studied law, was admitted to the bar in 1809, and practiced in Hyde Park, New York.

He was judge of Dutchess County, New York from 1830 to 1840. He was elected as an Anti-Jacksonian to the Twenty-second Congress (March 4, 1831 – March 4, 1833). He died in New York City on February 25, 1862, and was interred in St. James' Churchyard in Hyde Park.