Epinastine (brand names Alesion, Elestat, Purivist, Relestat) is a second-generation antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is produced by Allergan and marketed by Inspire in the United States.[1] It is highly selective for the H1 receptor and does not cross the blood-brain-barrier.[2]
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Trade names | Alesion, Elestat, Purivist, Relestat |
AHFS/Drugs.com | Monograph |
MedlinePlus | a604011 |
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Routes of administration | Eye drops |
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Pharmacokinetic data | |
Protein binding | 64% |
Elimination half-life | 12 hours |
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ECHA InfoCard | 100.120.187 |
Chemical and physical data | |
Formula | C16H15N3 |
Molar mass | 249.317 g·mol−1 |
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It was patented in 1980 and came into medical use in 1994.[3]