Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific), also known as FUT4, is an enzyme which in humans is encoded by the FUT4 gene.[1][2][3]
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) | |||||||
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Identifiers | |||||||
Symbol | FUT4 | ||||||
Alt. symbols | CD15, FCT3A, ELFT, SSEA-1, LeX | ||||||
NCBI gene | 2526 | ||||||
HGNC | 4015 | ||||||
OMIM | 104230 | ||||||
RefSeq | NM_002033 | ||||||
UniProt | P22083 | ||||||
Other data | |||||||
EC number | 2.4.1.152 | ||||||
Locus | Chr. 11 q21 | ||||||
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The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).[4][5]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.