Felbinac

Summary

Felbinac (INN, or biphenylylacetic acid) is a topical medicine,[1] belonging to the family of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs) of the arylacetic acid (not arylpropionic acid) class, which is used to treat muscle inflammation and arthritis.[2] It is an active metabolite of fenbufen.[3]

Felbinac
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Topical
ATC code
Legal status
Legal status
Identifiers
  • biphenyl-4-ylacetic acid
CAS Number
  • 5728-52-9
PubChem CID
  • 3332
DrugBank
  • DB07477 checkY
ChemSpider
  • 3215 checkY
UNII
  • 94WNJ5U8L7
KEGG
  • D01675 checkY
ChEBI
  • CHEBI:31597 checkY
ChEMBL
  • ChEMBL413965 checkY
CompTox Dashboard (EPA)
  • DTXSID0045389 Edit this at Wikidata
ECHA InfoCard100.024.758 Edit this at Wikidata
Chemical and physical data
FormulaC14H12O2
Molar mass212.248 g·mol−1
3D model (JSmol)
  • Interactive image
  • O=C(O)Cc1ccc(cc1)c2ccccc2
  • InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) checkY
  • Key:QRZAKQDHEVVFRX-UHFFFAOYSA-N checkY
  (verify)

Related compounds edit

The α-methyl acid of felbinac is called biprofen and is used to prepare bifepramide. The α-ethyl acid is called xenbucin which is used to make xenthiorate.

See also edit

References edit

  1. ^ The Merck Index, 12th Edition. 3989
  2. ^ Description of Felbinac on Tiscali [1]
  3. ^ Kohler C, Tolman E, Wooding W, Ellenbogen L (1980). "A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function". Arzneimittelforschung. 30 (4A): 702–707. PMID 6254545.