Fourphit Knowpia

Fourphit
Names
	Preferred IUPAC name 4-Isothiocyanato-1-(1-phenylcyclohexyl)piperidine
Identifiers
CAS Number	104639-01-2 ;
3D model (JSmol)	Interactive image;
ChemSpider	113988;
PubChem CID	128615;
UNII	EP455HL5XL ;
CompTox Dashboard (EPA)	DTXSID10146625 ;
	InChI InChI=1S/C18H24N2S/c21-15-19-17-9-13-20(14-10-17)18(11-5-2-6-12-18)16-7-3-1-4-8-16/h1,3-4,7-8,17H,2,5-6,9-14H2 Key: QAHYIAVTWZVTMY-UHFFFAOYSA-N; InChI=1/C18H24N2S/c21-15-19-17-9-13-20(14-10-17)18(11-5-2-6-12-18)16-7-3-1-4-8-16/h1,3-4,7-8,17H,2,5-6,9-14H2 Key: QAHYIAVTWZVTMY-UHFFFAOYAR;
	SMILES c1ccc(cc1)C2(CCCCC2)N3CCC(CC3)N=C=S;
Properties
Chemical formula	C18H24N2S
Molar mass	300.46 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Fourphit (4-isothiocyanato-1-[1-phenylcyclohexyl]piperidine) is a covalent binding NMDA antagonist, dopaminergic and sigma receptor agonist.^[1]

References edit

^ Schweri, M. M.; De Costa, B. R.; Rice, K. C. (1998). "Fourphit, an acylating phencyclidine derivative, attenuates cocaine-induced hyperactivity in rats". Pharmacology Biochemistry and Behavior. 60 (3): 615–23. doi:10.1016/s0091-3057(98)00040-9. PMID 9678644. S2CID 1151532.