A native of Savona, Lamperti attended the Milan Conservatory where, beginning in 1850, he taught for a quarter of a century. He was director at the Teatro Filodrammatico in Lodi. In 1875, he left the school and began to teach as a private tutor. Among his pupils were Sophie Cruvelli, Emma Albani, Gottardo Aldighieri, Désirée Artôt, Sona Aslanova, Lillie Berg, David Bispham, Italo Campanini, Virgilio Collini, Samuel Silas Curry, Franz Ferenczy, Friederike Grün, Teresa Stolz, Marie van Zandt, Maria Waldmann, Herbert Witherspoon, Tecla Vigna, and Lizzie Graham.^[2] See: List of music students by teacher: K to M#Francesco Lamperti. His methods were very similar to older Italian methods, and he wrote a number of treatises on the subject.

Lamperti was created a Commander of the Crown of Italy for his services to music.

His son Giovanni Battista Lamperti (1839–1910) was also a well-known voice teacher. He died in Como, Lombard on 1 May 1892

• Guida teorico-pratica-elementare per lo studio del canto. Milan: Ricordi, 1864.
• Studi di bravura per soprano. Translated as Studies in bravura singing for the soprano voice. New York: 1875.
• Esercizi giornalieri per soprano o mezzo-soprano
• L'arte del canto. Milan: Ricordi, 1883.
• Osservazioni e consigli sul trillo
• Solfeggi. Translated as Art of Singing by J. C. Griffith. London: Ricordi, 1877. Revised edition: New York: Edward Schuberth, 1890. (There also may be an edition by G. Schirmer).

• David Ewen, Encyclopedia of the Opera: New Enlarged Edition. New York; Hill and Wang, 1963.
• Baker's Biographical Dictionary of Musicians, (Nicolas Slonimsky, Ed.) New York: G. Schirmer, 1958.

• Free scores by Francesco Lamperti at the International Music Score Library Project (IMSLP)