GR-113808 is a drug which acts as a potent and selective 5-HT4 serotonin receptor antagonist.[1] It is used in researching the roles of 5-HT4 receptors in various processes,[2] and has been used to test some of the proposed therapeutic effects of selective 5-HT4 agonists, such as for instance blocking the nootropic effects of 5-HT4 agonists,[3][4] and worsening the respiratory depression produced by opioid analgesic drugs, which appears to be partly 5-HT4 mediated and can be counteracted by certain 5-HT4 agonists.[5]
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Formula | C19H27N3O4S |
Molar mass | 393.50 g·mol−1 |
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